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Antisense RNA directed to the human papillomavirus type 16 E7 mRNA from herpes simplex virus type 1 derived vectors is expressed in CaSki cells and downregulates E7 mRNA

BACKGROUND: Human papillomavirus (HPV) infection is known to be the most important etiologic factor of cervical cancer. There is no HPV specific therapy available for treatment of invasive squamous cell carcinoma of the cervix and its precursor lesions. The present study elucidates the potential to...

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Detalles Bibliográficos
Autores principales: Kari, Ilkka, Syrjänen, Stina, Johansson, Bo, Peri, Piritta, He, Bin, Roizman, Bernard, Hukkanen, Veijo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1892547/
https://www.ncbi.nlm.nih.gov/pubmed/17547759
http://dx.doi.org/10.1186/1743-422X-4-47