PINK1 Protects against Oxidative Stress by Phosphorylating Mitochondrial Chaperone TRAP1

Mutations in the PTEN induced putative kinase 1 (PINK1) gene cause an autosomal recessive form of Parkinson disease (PD). So far, no substrates of PINK1 have been reported, and the mechanism by which PINK1 mutations lead to neurodegeneration is unknown. Here we report the identification of TNF recep...

Descripción completa

Detalles Bibliográficos
Autores principales: Pridgeon, Julia W, Olzmann, James A, Chin, Lih-Shen, Li, Lian
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1892574/
https://www.ncbi.nlm.nih.gov/pubmed/17579517
http://dx.doi.org/10.1371/journal.pbio.0050172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1892574/
https://www.ncbi.nlm.nih.gov/pubmed/17579517
http://dx.doi.org/10.1371/journal.pbio.0050172

Ejemplares similares