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PINK1 Protects against Oxidative Stress by Phosphorylating Mitochondrial Chaperone TRAP1
Mutations in the PTEN induced putative kinase 1 (PINK1) gene cause an autosomal recessive form of Parkinson disease (PD). So far, no substrates of PINK1 have been reported, and the mechanism by which PINK1 mutations lead to neurodegeneration is unknown. Here we report the identification of TNF recep...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1892574/ https://www.ncbi.nlm.nih.gov/pubmed/17579517 http://dx.doi.org/10.1371/journal.pbio.0050172 |