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No Influence of Indy on Lifespan in Drosophila after Correction for Genetic and Cytoplasmic Background Effects

To investigate whether alterations in mitochondrial metabolism affect longevity in Drosophila melanogaster, we studied lifespan in various single gene mutants, using inbred and outbred genetic backgrounds. As positive controls we included the two most intensively studied mutants of Indy, which encod...

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Detalles Bibliográficos
Autores principales: Toivonen, Janne M, Walker, Glenda A, Martinez-Diaz, Pedro, Bjedov, Ivana, Driege, Yasmine, Jacobs, Howard T, Gems, David, Partridge, Linda
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1892600/
https://www.ncbi.nlm.nih.gov/pubmed/17571923
http://dx.doi.org/10.1371/journal.pgen.0030095