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A recessive genetic screen for host factors required for retroviral infection in a library of insertionally mutated Blm-deficient embryonic stem cells

BACKGROUND: Host factors required for retroviral infection are potential targets for the modulation of diseases caused by retroviruses. During the retroviral life cycle, numerous cellular factors interact with the virus and play an essential role in infection. Cultured embryonic stem (ES) cells are...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Bradley, Allan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1895998/
https://www.ncbi.nlm.nih.gov/pubmed/17407599
http://dx.doi.org/10.1186/gb-2007-8-4-r48