CAG-encoded polyglutamine length polymorphism in the human genome

BACKGROUND: Expansion of polyglutamine-encoding CAG trinucleotide repeats has been identified as the pathogenic mutation in nine different genes associated with neurodegenerative disorders. The majority of individuals clinically diagnosed with spinocerebellar ataxia do not have mutations within know...

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Detalles Bibliográficos
Autores principales: Butland, Stefanie L, Devon, Rebecca S, Huang, Yong, Mead, Carri-Lyn, Meynert, Alison M, Neal, Scott J, Lee, Soo Sen, Wilkinson, Anna, Yang, George S, Yuen, Macaire MS, Hayden, Michael R, Holt, Robert A, Leavitt, Blair R, Ouellette, BF Francis
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1896166/
https://www.ncbi.nlm.nih.gov/pubmed/17519034
http://dx.doi.org/10.1186/1471-2164-8-126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1896166/
https://www.ncbi.nlm.nih.gov/pubmed/17519034
http://dx.doi.org/10.1186/1471-2164-8-126

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