Lymphocytes and the Dap12 Adaptor Are Key Regulators of Osteoclast Activation Associated with Gonadal Failure

Bone resorption by osteoclasts is necessary to maintain bone homeostasis. Osteoclast differentiation from hematopoietic progenitors and their activation depend on M-CSF and RANKL, but also requires co-stimulatory signals acting through receptors associated with DAP12 and FcRγ adaptors. Dap12 mutant...

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Detalles Bibliográficos
Autores principales: Anginot, Adrienne, Dacquin, Romain, Mazzorana, Marlène, Jurdic, Pierre
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1899087/
https://www.ncbi.nlm.nih.gov/pubmed/17611620
http://dx.doi.org/10.1371/journal.pone.0000585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1899087/
https://www.ncbi.nlm.nih.gov/pubmed/17611620
http://dx.doi.org/10.1371/journal.pone.0000585

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