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Induction of lung lesions in Wistar rats by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and its inhibition by aspirin and phenethyl isothiocyanate

BACKGROUND: The development of effective chemopreventive agents against cigarette smoke-induced lung cancer could be greatly facilitated by suitable laboratory animal models, such as animals treated with the tobacco-specific lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). In th...

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Detalles Bibliográficos
Autores principales: Ye, Bo, Zhang, Yu-Xia, Yang, Fei, Chen, Hong-Lei, Xia, Dong, Liu, Ming-Qiu, Lai, Bai-Tang
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1899177/
https://www.ncbi.nlm.nih.gov/pubmed/17535415
http://dx.doi.org/10.1186/1471-2407-7-90