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Comparative sequence analysis of leucine-rich repeats (LRRs) within vertebrate toll-like receptors

BACKGROUND: Toll-like receptors (TLRs) play a central role in innate immunity. TLRs are membrane glycoproteins and contain leucine rich repeat (LRR) motif in the ectodomain. TLRs recognize and respond to molecules such as lipopolysaccharide, peptidoglycan, flagellin, and RNA from bacteria or viruses...

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Detalles Bibliográficos
Autores principales: Matsushima, Norio, Tanaka, Takanori, Enkhbayar, Purevjav, Mikami, Tomoko, Taga, Masae, Yamada, Keiko, Kuroki, Yoshio
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1899181/
https://www.ncbi.nlm.nih.gov/pubmed/17517123
http://dx.doi.org/10.1186/1471-2164-8-124