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The role of CDK in the initiation step of DNA replication in eukaryotes

Cyclin-dependent kinases (CDKs) regulate the progression of the cell cycle in eukaryotes. One of the major roles of CDK is to promote chromosomal DNA replication. However, how CDKs promote DNA replication has been a long-standing question, because all the essential CDK substrates in DNA replication...

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Detalles Bibliográficos
Autores principales: Tanaka, Seiji, Tak, Yon-Soo, Araki, Hiroyuki
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1899495/
https://www.ncbi.nlm.nih.gov/pubmed/17547773
http://dx.doi.org/10.1186/1747-1028-2-16