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The NMR structure of the murine DLC2 SAM domain reveals a variant fold that is similar to a four-helix bundle

BACKGROUND: The tumor suppressor DLC2 (Deleted in Liver Cancer -2) participates in cell signaling at the mitochondrial membrane. DLC2 is characterized by a SAM (sterile alpha motif) domain, a Rho GTPase activating protein (GAP) domain, and a START lipid transfer domain. RESULTS: Towards understandin...

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Detalles Bibliográficos
Autores principales: Kwan, Jamie J, Donaldson, Logan W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1899508/
https://www.ncbi.nlm.nih.gov/pubmed/17519008
http://dx.doi.org/10.1186/1472-6807-7-34