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The NMR structure of the murine DLC2 SAM domain reveals a variant fold that is similar to a four-helix bundle
BACKGROUND: The tumor suppressor DLC2 (Deleted in Liver Cancer -2) participates in cell signaling at the mitochondrial membrane. DLC2 is characterized by a SAM (sterile alpha motif) domain, a Rho GTPase activating protein (GAP) domain, and a START lipid transfer domain. RESULTS: Towards understandin...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2007
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1899508/ https://www.ncbi.nlm.nih.gov/pubmed/17519008 http://dx.doi.org/10.1186/1472-6807-7-34 |