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Metabolic compartmentalization in the human cortex and hippocampus: evidence for a cell- and region-specific localization of lactate dehydrogenase 5 and pyruvate dehydrogenase

BACKGROUND: For a long time now, glucose has been thought to be the main, if not the sole substrate for brain energy metabolism. Recent data nevertheless suggest that other molecules, such as monocarboxylates (lactate and pyruvate mainly) could be suitable substrates. Although monocarboxylates poorl...

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Detalles Bibliográficos
Autores principales: Laughton, Jocelyn D, Bittar, Philippe, Charnay, Yves, Pellerin, Luc, Kovari, Enikö, Magistretti, Pierre J, Bouras, Constantin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1899510/
https://www.ncbi.nlm.nih.gov/pubmed/17521432
http://dx.doi.org/10.1186/1471-2202-8-35