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Using RNA secondary structures to guide sequence motif finding towards single-stranded regions

RNA binding proteins recognize RNA targets in a sequence specific manner. Apart from the sequence, the secondary structure context of the binding site also affects the binding affinity. Binding sites are often located in single-stranded RNA regions and it was shown that the sequestration of a bindin...

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Detalles Bibliográficos
Autores principales: Hiller, Michael, Pudimat, Rainer, Busch, Anke, Backofen, Rolf
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1903381/
https://www.ncbi.nlm.nih.gov/pubmed/16987907
http://dx.doi.org/10.1093/nar/gkl544