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Replacement of the essential Dictyostelium Arp2 gene by its Entamoeba homologue using parasexual genetics

BACKGROUND: Cell motility is an essential feature of the pathogenesis and morbidity of amoebiasis caused by Entamoeba histolytica. As motility depends on cytoskeletal organisation and regulation, a study of the molecular components involved is key to a better understanding of amoebic pathogenesis. H...

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Detalles Bibliográficos
Autores principales: Zaki, Mehreen, King, Jason, Fütterer, Klaus, Insall, Robert H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1904233/
https://www.ncbi.nlm.nih.gov/pubmed/17553170
http://dx.doi.org/10.1186/1471-2156-8-28