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Lentiviral vector design using alternative RNA export elements

BACKGROUND: Lentiviral vectors have been designed with complex RNA export sequences in both the integrating and packaging plasmids in order to co-ordinate efficient vector production. Recent studies have attempted to replace the existing complex rev/RRE system with a more simplistic RNA export syste...

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Detalles Bibliográficos
Autores principales: Oh, Taekeun, Bajwa, Ali, Jia, Guangfu, Park, Frank
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1904242/
https://www.ncbi.nlm.nih.gov/pubmed/17550606
http://dx.doi.org/10.1186/1742-4690-4-38