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Discovering functional linkages and uncharacterized cellular pathways using phylogenetic profile comparisons: a comprehensive assessment

BACKGROUND: A widely-used approach for discovering functional and physical interactions among proteins involves phylogenetic profile comparisons (PPCs). Here, proteins with similar profiles are inferred to be functionally related under the assumption that proteins involved in the same metabolic path...

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Detalles Bibliográficos
Autores principales: Jothi, Raja, Przytycka, Teresa M, Aravind, L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1904249/
https://www.ncbi.nlm.nih.gov/pubmed/17521444
http://dx.doi.org/10.1186/1471-2105-8-173