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Modulating the Expression of Disease Genes with RNA-Based Therapy

Conventional gene therapy has focused largely on gene replacement in target cells. However, progress from basic research to the clinic has been slow for reasons relating principally to the challenges of heterologous DNA delivery and regulation in vivo. Alternative approaches targeting RNA have the p...

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Detalles Bibliográficos
Autores principales: Wood, Matthew, Yin, Haifang, McClorey, Graham
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1904251/
https://www.ncbi.nlm.nih.gov/pubmed/17604456
http://dx.doi.org/10.1371/journal.pgen.0030109