Theoretical study of large conformational transitions in DNA: the B↔A conformational change in water and ethanol/water

We explore here the possibility of determining theoretically the free energy change associated with large conformational transitions in DNA, like the solvent-induced B⇔A conformational change. We find that a combination of targeted molecular dynamics (tMD) and the weighted histogram analysis method...

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Detalles Bibliográficos
Autores principales: Noy, Agnes, Pérez, Alberto, Laughton, Charles A., Orozco, Modesto
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1904281/
https://www.ncbi.nlm.nih.gov/pubmed/17459891
http://dx.doi.org/10.1093/nar/gkl1135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1904281/
https://www.ncbi.nlm.nih.gov/pubmed/17459891
http://dx.doi.org/10.1093/nar/gkl1135

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