DNA sequence-specific recognition by a transcriptional regulator requires indirect readout of A-tracts

The bacteriophage Ø29 transcriptional regulator p4 binds to promoters of different intrinsic activities. The p4–DNA complex contains two identical protomers that make similar interactions with the target sequence 5′-AACTTTTT-15 bp-AAAATGTT-3′. To define how the various elements in the target sequenc...

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Detalles Bibliográficos
Autores principales: Mendieta, Jesús, Pérez-Lago, Laura, Salas, Margarita, Camacho, Ana
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1904284/
https://www.ncbi.nlm.nih.gov/pubmed/17452358
http://dx.doi.org/10.1093/nar/gkm180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1904284/
https://www.ncbi.nlm.nih.gov/pubmed/17452358
http://dx.doi.org/10.1093/nar/gkm180

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