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Sequences in attB that affect the ability of ϕC31 integrase to synapse and to activate DNA cleavage

Phage integrases are required for recombination of the phage genome with the host chromosome either to establish or exit from the lysogenic state. ϕC31 integrase is a member of the serine recombinase family of site-specific recombinases. In the absence of any accessory factors integrase is unidirect...

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Detalles Bibliográficos
Autores principales: Gupta, Milind, Till, Rob, Smith, Margaret C. M.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1904298/
https://www.ncbi.nlm.nih.gov/pubmed/17478521
http://dx.doi.org/10.1093/nar/gkm206