Chaperone-based procedure to increase yields of soluble recombinant proteins produced in E. coli

BACKGROUND: The overproduction of recombinant proteins in host cells often leads to their misfolding and aggregation. Previous attempts to increase the solubility of recombinant proteins by co-overproduction of individual chaperones were only partially successful. We now assessed the effects of comb...

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Detalles Bibliográficos
Autores principales: de Marco, Ario, Deuerling, Elke, Mogk, Axel, Tomoyasu, Toshifumi, Bukau, Bernd
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1904446/
https://www.ncbi.nlm.nih.gov/pubmed/17565681
http://dx.doi.org/10.1186/1472-6750-7-32

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1904446/
https://www.ncbi.nlm.nih.gov/pubmed/17565681
http://dx.doi.org/10.1186/1472-6750-7-32

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