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Chaperone-based procedure to increase yields of soluble recombinant proteins produced in E. coli

BACKGROUND: The overproduction of recombinant proteins in host cells often leads to their misfolding and aggregation. Previous attempts to increase the solubility of recombinant proteins by co-overproduction of individual chaperones were only partially successful. We now assessed the effects of comb...

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Detalles Bibliográficos
Autores principales:	de Marco, Ario, Deuerling, Elke, Mogk, Axel, Tomoyasu, Toshifumi, Bukau, Bernd
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1904446/ https://www.ncbi.nlm.nih.gov/pubmed/17565681 http://dx.doi.org/10.1186/1472-6750-7-32

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