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Changes in var gene mRNA levels during erythrocytic development in two phenotypically distinct Plasmodium falciparum parasites

BACKGROUND: The var multigene family encodes PfEMP1, which are expressed on the surface of infected erythrocytes and bind to various host endothelial receptors. Antigenic variation of PfEMP1 plays a key role in malaria pathogenesis, a process partially controlled at the level of var gene transcripti...

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Detalles Bibliográficos
Autores principales: Dahlbäck, Madeleine, Lavstsen, Thomas, Salanti, Ali, Hviid, Lars, Arnot, David E, Theander, Thor G, Nielsen, Morten A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1904452/
https://www.ncbi.nlm.nih.gov/pubmed/17565661
http://dx.doi.org/10.1186/1475-2875-6-78