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Changes in var gene mRNA levels during erythrocytic development in two phenotypically distinct Plasmodium falciparum parasites
BACKGROUND: The var multigene family encodes PfEMP1, which are expressed on the surface of infected erythrocytes and bind to various host endothelial receptors. Antigenic variation of PfEMP1 plays a key role in malaria pathogenesis, a process partially controlled at the level of var gene transcripti...
Autores principales: | Dahlbäck, Madeleine, Lavstsen, Thomas, Salanti, Ali, Hviid, Lars, Arnot, David E, Theander, Thor G, Nielsen, Morten A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1904452/ https://www.ncbi.nlm.nih.gov/pubmed/17565661 http://dx.doi.org/10.1186/1475-2875-6-78 |
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