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Differential expression and role of p21(cip/waf1 )and p27(kip1 )in TNF-α-induced inhibition of proliferation in human glioma cells
BACKGROUND: The role of TNF-α in affecting the fate of tumors is controversial, while some studies have reported apoptotic or necrotic effects of TNF-α, others provide evidence that endogenous TNF-α promotes growth and development of tumors. Understanding the mechanism(s) of TNF-α mediated growth ar...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1904457/ https://www.ncbi.nlm.nih.gov/pubmed/17565690 http://dx.doi.org/10.1186/1476-4598-6-42 |