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Evidence of Differential HLA Class I-Mediated Viral Evolution in Functional and Accessory/Regulatory Genes of HIV-1

Despite the formidable mutational capacity and sequence diversity of HIV-1, evidence suggests that viral evolution in response to specific selective pressures follows generally predictable mutational pathways. Population-based analyses of clinically derived HIV sequences may be used to identify immu...

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Detalles Bibliográficos
Autores principales: Brumme, Zabrina L, Brumme, Chanson J, Heckerman, David, Korber, Bette T, Daniels, Marcus, Carlson, Jonathan, Kadie, Carl, Bhattacharya, Tanmoy, Chui, Celia, Szinger, James, Mo, Theresa, Hogg, Robert S, Montaner, Julio S. G, Frahm, Nicole, Brander, Christian, Walker, Bruce D, Harrigan, P. Richard
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1904471/
https://www.ncbi.nlm.nih.gov/pubmed/17616974
http://dx.doi.org/10.1371/journal.ppat.0030094