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Evidence of Differential HLA Class I-Mediated Viral Evolution in Functional and Accessory/Regulatory Genes of HIV-1
Despite the formidable mutational capacity and sequence diversity of HIV-1, evidence suggests that viral evolution in response to specific selective pressures follows generally predictable mutational pathways. Population-based analyses of clinically derived HIV sequences may be used to identify immu...
Autores principales: | Brumme, Zabrina L, Brumme, Chanson J, Heckerman, David, Korber, Bette T, Daniels, Marcus, Carlson, Jonathan, Kadie, Carl, Bhattacharya, Tanmoy, Chui, Celia, Szinger, James, Mo, Theresa, Hogg, Robert S, Montaner, Julio S. G, Frahm, Nicole, Brander, Christian, Walker, Bruce D, Harrigan, P. Richard |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1904471/ https://www.ncbi.nlm.nih.gov/pubmed/17616974 http://dx.doi.org/10.1371/journal.ppat.0030094 |
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