The N terminus of the serpin, tengpin, functions to trap the metastable native state

Serpins fold to a metastable native state and are susceptible to undergoing spontaneous conformational change to more stable conformers, such as the latent form. We investigated conformational change in tengpin, an unusual prokaryotic serpin from the extremophile Thermoanaerobacter tengcongensis. In...

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Detalles Bibliográficos
Autores principales: Zhang, Qingwei, Buckle, Ashley M, Law, Ruby H P, Pearce, Mary C, Cabrita, Lisa D, Lloyd, Gordon J, Irving, James A, Smith, A Ian, Ruzyla, Katya, Rossjohn, Jamie, Bottomley, Stephen P, Whisstock, James C
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Scientific Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1905895/
https://www.ncbi.nlm.nih.gov/pubmed/17557112
http://dx.doi.org/10.1038/sj.embor.7400986

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1905895/
https://www.ncbi.nlm.nih.gov/pubmed/17557112
http://dx.doi.org/10.1038/sj.embor.7400986

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