Cargando…
The N terminus of the serpin, tengpin, functions to trap the metastable native state
Serpins fold to a metastable native state and are susceptible to undergoing spontaneous conformational change to more stable conformers, such as the latent form. We investigated conformational change in tengpin, an unusual prokaryotic serpin from the extremophile Thermoanaerobacter tengcongensis. In...
| Autores principales: | , , , , , , , , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2007
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1905895/ https://www.ncbi.nlm.nih.gov/pubmed/17557112 http://dx.doi.org/10.1038/sj.embor.7400986 |