Efficient and Specific Internal Cleavage of a Retroviral Palindromic DNA Sequence by Tetrameric HIV-1 Integrase

BACKGROUND: HIV-1 integrase (IN) catalyses the retroviral integration process, removing two nucleotides from each long terminal repeat and inserting the processed viral DNA into the target DNA. It is widely assumed that the strand transfer step has no sequence specificity. However, recently, it has...

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Detalles Bibliográficos
Autores principales: Delelis, Olivier, Parissi, Vincent, Leh, Hervé, Mbemba, Gladys, Petit, Caroline, Sonigo, Pierre, Deprez, Eric, Mouscadet, Jean-François
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1905944/
https://www.ncbi.nlm.nih.gov/pubmed/17622353
http://dx.doi.org/10.1371/journal.pone.0000608

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1905944/
https://www.ncbi.nlm.nih.gov/pubmed/17622353
http://dx.doi.org/10.1371/journal.pone.0000608

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