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Specific expression of lacZ and cre recombinase in fetal thymic epithelial cells by multiplex gene targeting at the Foxn1 locus

BACKGROUND: Thymic epithelial cells (TECs) promote thymocyte maturation and are required for the early stages of thymocyte development and for positive selection. However, investigation of the mechanisms by which TECs perform these functions has been inhibited by the lack of genetic tools. Since the...

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Detalles Bibliográficos
Autores principales: Gordon, Julie, Xiao, Shiyun, Hughes, Bernard, Su, Dong-ming, Navarre, Samuel P, Condie, Brian G, Manley, Nancy R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1906761/
https://www.ncbi.nlm.nih.gov/pubmed/17577402
http://dx.doi.org/10.1186/1471-213X-7-69