Rheumatoid peripheral blood phagocytes are primed for activation but have impaired Fc-mediated generation of reactive oxygen species

Significant levels of circulating immune complexes (ICs) containing rheumatoid factors and immunoglobulin G in peripheral blood are a characteristic feature of rheumatoid arthritis (RA). ICs interact through Fcγ receptors (FcγR) to activate phagocytes in numerous inflammatory processes. The high con...

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Detalles Bibliográficos
Autores principales: Fairhurst, Anna-Marie, Wallace, Paul K, Jawad, Ali SM, Goulding, Nicolas J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1906807/
https://www.ncbi.nlm.nih.gov/pubmed/17355628
http://dx.doi.org/10.1186/ar2144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1906807/
https://www.ncbi.nlm.nih.gov/pubmed/17355628
http://dx.doi.org/10.1186/ar2144

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