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Altered phenotype and gene transcription in endothelial cells, induced by Plasmodium falciparum-infected red blood cells: Pathogenic or protective?

Severe malaria is associated with sequestration of Plasmodium falciparum-infected red blood cells (PRBC) in the microvasculature and elevation of intercellular adhesion molecule-1 (ICAM-1) and TNF. In vitro co-culture of human umbilical vein endothelial cells (HUVEC), with either PRBC or uninfected...

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Detalles Bibliográficos
Autores principales: Chakravorty, Srabasti J., Carret, Celine, Nash, Gerard B., Ivens, Al, Szestak, Tadge, Craig, Alister G.
Formato: Texto
Lenguaje:English
Publicado: Elsevier Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1906861/
https://www.ncbi.nlm.nih.gov/pubmed/17383656
http://dx.doi.org/10.1016/j.ijpara.2007.02.006