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The Role of Rab3a in Secretory Vesicle Docking Requires Association/Dissociation of Guanidine Phosphates and Munc18-1
Rab3a is a small GTPase that binds selectively to secretory vesicles and switches between active, GTP-bound and inactive, GDP-bound conformations. In yeast, Rab and SM-genes interact genetically to promote vesicle targeting/fusion. We tested different Rab3a conformations and genetic interactions wit...
Autores principales: | van Weering, Jan R.T., Toonen, Ruud F., Verhage, Matthijs |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1910611/ https://www.ncbi.nlm.nih.gov/pubmed/17637832 http://dx.doi.org/10.1371/journal.pone.0000616 |
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