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Genetic Association Mapping via Evolution-Based Clustering of Haplotypes
Multilocus analysis of single nucleotide polymorphism haplotypes is a promising approach to dissecting the genetic basis of complex diseases. We propose a coalescent-based model for association mapping that potentially increases the power to detect disease-susceptibility variants in genetic associat...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1913101/ https://www.ncbi.nlm.nih.gov/pubmed/17616979 http://dx.doi.org/10.1371/journal.pgen.0030111 |