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Genetic Association Mapping via Evolution-Based Clustering of Haplotypes

Multilocus analysis of single nucleotide polymorphism haplotypes is a promising approach to dissecting the genetic basis of complex diseases. We propose a coalescent-based model for association mapping that potentially increases the power to detect disease-susceptibility variants in genetic associat...

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Detalles Bibliográficos
Autores principales: Tachmazidou, Ioanna, Verzilli, Claudio J, Iorio, Maria De
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1913101/
https://www.ncbi.nlm.nih.gov/pubmed/17616979
http://dx.doi.org/10.1371/journal.pgen.0030111