Genetic variants of chemokine receptor CCR7 in patients with systemic lupus erythematosus, Sjogren's syndrome and systemic sclerosis

BACKGROUND: The chemokine receptor CCR7 is a key organizer of the immune system. Gene targeting in mice revealed that Ccr7-deficient animals are severely impaired in the induction of central and peripheral tolerance. Due to these defects, Ccr7-deficient mice spontaneously develop multi-organ autoimm...

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Detalles Bibliográficos
Autores principales: Kahlmann, Daniel, Davalos-Misslitz, Ana Clara Marques, Ohl, Lars, Stanke, Frauke, Witte, Torsten, Förster, Reinhold
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1913537/
https://www.ncbi.nlm.nih.gov/pubmed/17587445
http://dx.doi.org/10.1186/1471-2156-8-33

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1913537/
https://www.ncbi.nlm.nih.gov/pubmed/17587445
http://dx.doi.org/10.1186/1471-2156-8-33

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