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Expression of LIM kinase 1 is associated with reversible G1/S phase arrest, chromosomal instability and prostate cancer

BACKGROUND: LIM kinase 1 (LIMK1), a LIM domain containing serine/threonine kinase, modulates actin dynamics through inactivation of the actin depolymerizing protein cofilin. Recent studies have indicated an important role of LIMK1 in growth and invasion of prostate and breast cancer cells; however,...

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Detalles Bibliográficos
Autores principales: Davila, Monica, Jhala, Darshana, Ghosh, Debashis, Grizzle, William E, Chakrabarti, Ratna
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1913540/
https://www.ncbi.nlm.nih.gov/pubmed/17559677
http://dx.doi.org/10.1186/1476-4598-6-40