Cargando…

Expression of LIM kinase 1 is associated with reversible G1/S phase arrest, chromosomal instability and prostate cancer

BACKGROUND: LIM kinase 1 (LIMK1), a LIM domain containing serine/threonine kinase, modulates actin dynamics through inactivation of the actin depolymerizing protein cofilin. Recent studies have indicated an important role of LIMK1 in growth and invasion of prostate and breast cancer cells; however,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Davila, Monica, Jhala, Darshana, Ghosh, Debashis, Grizzle, William E, Chakrabarti, Ratna
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1913540/ https://www.ncbi.nlm.nih.gov/pubmed/17559677 http://dx.doi.org/10.1186/1476-4598-6-40

Ejemplares similares

LIM kinase1 modulates function of membrane type matrix metalloproteinase 1: implication in invasion of prostate cancer cells
por: Tapia, Tenekua, et al.
Publicado: (2011)

Joint Variable Selection and Classification with Immunohistochemical Data
por: Ghosh, Debashis, et al.
Publicado: (2009)

LIM kinases: cofilin and beyond
por: Prunier, Chloé, et al.
Publicado: (2017)

LIM Kinases in Osteosarcoma Development
por: Brion, Régis, et al.
Publicado: (2021)

Downregulation of LIM kinase 1 suppresses ocular inflammation and fibrosis
por: Gorovoy, Matvey, et al.
Publicado: (2008)

The other face of miR-17-92a cluster, exhibiting tumor suppressor effects in prostate cancer
por: Ottman, Richard, et al.
Publicado: (2016)

Targeting LIM kinase in cancer and neurofibromatosis
por: Rak, Roni, et al.
Publicado: (2014)

ROCK1 via LIM kinase regulates growth, maturation and actin based functions in mast cells
por: Kapur, Reuben, et al.
Publicado: (2016)

Targeting LIM kinases in taxane resistant tumors
por: Prunier, Chloé, et al.
Publicado: (2016)

The Role of LIM Kinase in the Male Urogenital System
por: Park, Juhyun, et al.
Publicado: (2021)

LIM Kinases: From Molecular to Pathological Features
por: Bénédetti, Hélène, et al.
Publicado: (2023)

Mutation of NIMA-related kinase 1 (NEK1) leads to chromosome instability
por: Chen, Yumay, et al.
Publicado: (2011)

Involvement of LIM kinase 1 in actin polarization in human CD4 T cells
por: Xu, Xuehua, et al.
Publicado: (2012)

LIM kinase 1 serves an important role in the multidrug resistance of osteosarcoma cells
por: Yang, Jian-Zeng, et al.
Publicado: (2018)

The abnormal phosphorylation of the Rac1, Lim-kinase 1, and Cofilin proteins in the pathogenesis of Hirschsprung’s disease
por: Zhou, Wan-Kang, et al.
Publicado: (2022)

A cold scare: Formation of cold reactive anti-A1 coinciding with gross hemolysis
por: Petersen, Jeffrey, et al.
Publicado: (2018)

LIM kinases in synaptic plasticity and their potential as therapeutic targets
por: Halász, Éva, et al.
Publicado: (2020)

LIM-Kinases in Synaptic Plasticity, Memory, and Brain Diseases
por: Ben Zablah, Youssif, et al.
Publicado: (2021)

Palmitoylation of LIM Kinase-1 ensures spine-specific actin polymerization and morphological plasticity
por: George, Joju, et al.
Publicado: (2015)

Discovery of Novel Small-Molecule Inhibitors of LIM Domain Kinase for Inhibiting HIV-1
por: Yi, Fei, et al.
Publicado: (2017)

Drug resistance reversed by silencing LIM domain-containing protein 1 expression in colorectal carcinoma
por: CHEN, ZHANGXING, et al.
Publicado: (2014)

Kinase-independent role of cyclin D1 in chromosomal instability and mammary tumorigenesis
por: Casimiro, Mathew C., et al.
Publicado: (2015)

Doublecortin-like kinase 1 compromises DNA repair and induces chromosomal instability
por: Lu, Yuxiong, et al.
Publicado: (2018)

Aurora kinase B-phosphorylated HP1α functions in chromosomal instability
por: Williams, Monique M., et al.
Publicado: (2019)

FTO Knockout Causes Chromosome Instability and G2/M Arrest in Mouse GC-1 Cells
por: Huang, Tao, et al.
Publicado: (2019)

A role for cofilin and LIM kinase in Listeria-induced phagocytosis
por: Bierne, Hélène, et al.
Publicado: (2001)

The terminal basal mitosis of chicken retinal Lim1 horizontal cells is not sensitive to cisplatin-induced cell cycle arrest
por: Shirazi Fard, Shahrzad, et al.
Publicado: (2014)

LIM kinase 1 interacts with myosin-9 and alpha-actinin-4 and promotes colorectal cancer progression
por: Liao, Qing, et al.
Publicado: (2017)

LIM-kinase 1 effects on memory abilities and male courtship song in Drosophila depend on the neuronal type
por: Zhuravlev, A.V., et al.
Publicado: (2023)

LIM kinase 1 - dependent cofilin 1 pathway and actin dynamics mediate nuclear retinoid receptor function in T lymphocytes
por: Ishaq, Mohammad, et al.
Publicado: (2011)

Damnacanthal, an effective inhibitor of LIM-kinase, inhibits cell migration and invasion
por: Ohashi, Kazumasa, et al.
Publicado: (2014)

LIM Domain Kinases as Potential Therapeutic Targets for Neurofibromatosis Type 2
por: Petrilli, Alejandra, et al.
Publicado: (2013)

Inhibition of LIM kinase reduces contraction and proliferation in bladder smooth muscle
por: Yu, Qingfeng, et al.
Publicado: (2021)

Polo-Like Kinase 1 Regulates Chromosomal Instability and Paclitaxel Resistance in Breast Cancer Cells
por: Quan, Mingji, et al.
Publicado: (2022)

Localization of Reversion-Induced LIM Protein (RIL) in the Rat Central Nervous System
por: Iida, Yuko, et al.
Publicado: (2009)

LIM1 contributes to the malignant potential of endometrial cancer
por: Kato, Hiroaki, et al.
Publicado: (2023)

Rho-Associated Protein Kinase (ROCK) Promotes Proliferation and Migration of PC-3 and DU145 Prostate Cancer Cells by Targeting LIM Kinase 1 (LIMK1) and Matrix Metalloproteinase-2 (MMP-2)
por: Gong, Hua, et al.
Publicado: (2019)

LIM kinase1 regulates mitotic centrosome integrity via its activity on dynein light intermediate chains
por: Ou, Sirong, et al.
Publicado: (2018)

Cleavage and activation of LIM kinase 1 as a novel mechanism for calpain 2-mediated regulation of nuclear dynamics
por: Rodríguez-Fernández, L., et al.
Publicado: (2021)

LIM Kinases, LIMK1 and LIMK2, Are Crucial Node Actors of the Cell Fate: Molecular to Pathological Features
por: Villalonga, Elodie, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_ra8v0cbm1t83ph9rivn0fe76p6