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Comparison of miRNA expression patterns using total RNA extracted from matched samples of formalin-fixed paraffin-embedded (FFPE) cells and snap frozen cells

BACKGROUND: Archival formalin-fixed paraffin-embedded (FFPE) tissues have limited utility in applications involving analysis of gene expression due to mRNA degradation and modification during fixation and processing. This study analyzed 160 miRNAs in paired snap frozen and FFPE cells to investigate...

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Detalles Bibliográficos
Autores principales: Li, Jinghuan, Smyth, Paul, Flavin, Richard, Cahill, Susanne, Denning, Karen, Aherne, Sinead, Guenther, Simone M, O'Leary, John J, Sheils, Orla
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1914054/
https://www.ncbi.nlm.nih.gov/pubmed/17603869
http://dx.doi.org/10.1186/1472-6750-7-36