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Homocysteine affects cardiomyocyte viability: concentration-dependent effects on reversible flip-flop, apoptosis and necrosis

BACKGROUND: Hyperhomocysteinaemia (HHC) is thought to be a risk factor for cardiovascular disease including heart failure. While numerous studies have analyzed the role of homocysteine (Hcy) in the vasculature, only a few studies investigated the role of Hcy in the heart. Therefore we have analyzed...

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Detalles Bibliográficos
Autores principales: Sipkens, Jessica A., Krijnen, Paul A. J., Meischl, Christof, Cillessen, Saskia A. G. M., Smulders, Yvo M., Smith, Desirée E. C., Giroth, Cindy P. E., Spreeuwenberg, Marieke D., Musters, René J. P., Muller, Alice, Jakobs, Cornelis, Roos, Dirk, Stehouwer, Coen D. A., Rauwerda, Jan A., van Hinsbergh, Victor W. M., Niessen, Hans W. M.
Formato: Texto
Lenguaje:English
Publicado: Kluwer Academic Publishers-Plenum Publishers 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1914234/
https://www.ncbi.nlm.nih.gov/pubmed/17440815
http://dx.doi.org/10.1007/s10495-007-0077-5