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Homocysteine affects cardiomyocyte viability: concentration-dependent effects on reversible flip-flop, apoptosis and necrosis
BACKGROUND: Hyperhomocysteinaemia (HHC) is thought to be a risk factor for cardiovascular disease including heart failure. While numerous studies have analyzed the role of homocysteine (Hcy) in the vasculature, only a few studies investigated the role of Hcy in the heart. Therefore we have analyzed...
Autores principales: | Sipkens, Jessica A., Krijnen, Paul A. J., Meischl, Christof, Cillessen, Saskia A. G. M., Smulders, Yvo M., Smith, Desirée E. C., Giroth, Cindy P. E., Spreeuwenberg, Marieke D., Musters, René J. P., Muller, Alice, Jakobs, Cornelis, Roos, Dirk, Stehouwer, Coen D. A., Rauwerda, Jan A., van Hinsbergh, Victor W. M., Niessen, Hans W. M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Kluwer Academic Publishers-Plenum Publishers
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1914234/ https://www.ncbi.nlm.nih.gov/pubmed/17440815 http://dx.doi.org/10.1007/s10495-007-0077-5 |
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