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Mutational pattern and frequency of induced nucleotide changes in mouse ENU mutagenesis

BACKGROUND: With the advent of sequence-based approaches in the mutagenesis studies, it is now possible to directly evaluate the genome-wide pattern of experimentally induced DNA sequence changes for a diverse array of organisms. To gain a more comprehensive understanding of the mutational bias inhe...

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Detalles Bibliográficos
Autores principales: Takahasi, K Ryo, Sakuraba, Yoshiyuki, Gondo, Yoichi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1914352/
https://www.ncbi.nlm.nih.gov/pubmed/17584492
http://dx.doi.org/10.1186/1471-2199-8-52