Validation of a rapid, non-radioactive method to quantify internalisation of G-protein coupled receptors

Agonist exposure can cause internalisation of G-protein coupled receptors (GPCRs), which may be a part of desensitisation but also of cellular signaling. Previous methods to study internalisation have been tedious or only poorly quantitative. Therefore, we have developed and validated a quantitative...

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Detalles Bibliográficos
Autores principales: Jongsma, Maikel, Florczyk, Urszula M., Hendriks-Balk, Mariëlle C., Michel, Martin C., Peters, Stephan L. M., Alewijnse, Astrid E.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2007
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1915601/
https://www.ncbi.nlm.nih.gov/pubmed/17497135
http://dx.doi.org/10.1007/s00210-007-0164-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1915601/
https://www.ncbi.nlm.nih.gov/pubmed/17497135
http://dx.doi.org/10.1007/s00210-007-0164-8

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