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Validation of a rapid, non-radioactive method to quantify internalisation of G-protein coupled receptors
Agonist exposure can cause internalisation of G-protein coupled receptors (GPCRs), which may be a part of desensitisation but also of cellular signaling. Previous methods to study internalisation have been tedious or only poorly quantitative. Therefore, we have developed and validated a quantitative...
Autores principales: | Jongsma, Maikel, Florczyk, Urszula M., Hendriks-Balk, Mariëlle C., Michel, Martin C., Peters, Stephan L. M., Alewijnse, Astrid E. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1915601/ https://www.ncbi.nlm.nih.gov/pubmed/17497135 http://dx.doi.org/10.1007/s00210-007-0164-8 |
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