Human mass balance study of the novel anticancer agent ixabepilone using accelerator mass spectrometry

Ixabepilone (BMS-247550) is a semi-synthetic, microtubule stabilizing epothilone B analogue which is more potent than taxanes and has displayed activity in taxane-resistant patients. The human plasma pharmacokinetics of ixabepilone have been described. However, the excretory pathways and contributio...

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Detalles Bibliográficos
Autores principales: Beumer, J. H., Garner, R. C., Cohen, M. B., Galbraith, S., Duncan, G. F., Griffin, T., Beijnen, J. H., Schellens, J. H. M.
Formato: Texto
Lenguaje:English
Publicado: Kluwer Academic Publishers-Plenum Publishers 2007
Materias:
Phase I Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1915607/
https://www.ncbi.nlm.nih.gov/pubmed/17347871
http://dx.doi.org/10.1007/s10637-007-9041-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1915607/
https://www.ncbi.nlm.nih.gov/pubmed/17347871
http://dx.doi.org/10.1007/s10637-007-9041-z

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