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Human mass balance study of the novel anticancer agent ixabepilone using accelerator mass spectrometry

Ixabepilone (BMS-247550) is a semi-synthetic, microtubule stabilizing epothilone B analogue which is more potent than taxanes and has displayed activity in taxane-resistant patients. The human plasma pharmacokinetics of ixabepilone have been described. However, the excretory pathways and contributio...

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Detalles Bibliográficos
Autores principales:	Beumer, J. H., Garner, R. C., Cohen, M. B., Galbraith, S., Duncan, G. F., Griffin, T., Beijnen, J. H., Schellens, J. H. M.
Formato:	Texto
Lenguaje:	English
Publicado:	Kluwer Academic Publishers-Plenum Publishers 2007
Materias:	Phase I Studies
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1915607/ https://www.ncbi.nlm.nih.gov/pubmed/17347871 http://dx.doi.org/10.1007/s10637-007-9041-z

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