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Targeting 15d-Prostaglandin J(2) to Hepatic Stellate Cells: Two Options Evaluated

PURPOSE: Delivery of apoptosis-inducing compounds to hepatic stellate cells (HSC) may be an effective strategy to reverse liver fibrosis. The aim of this study was therefore to examine the selective targeting of the apoptosis-inducing drug 15-deoxy-Δ12,14-prostaglandin J(2) (15dPGJ(2)) with two diff...

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Detalles Bibliográficos
Autores principales: Hagens, Werner I., Mattos, Adriana, Greupink, Rick, de Jager-Krikken, Alie, Reker-Smit, Catharina, van Loenen-Weemaes, AnneMiek, Gouw, Annette S. H., Poelstra, Klaas, Beljaars, Leonie
Formato: Texto
Lenguaje:English
Publicado: Kluwer Academic Publishers-Plenum Publishers 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1915609/
https://www.ncbi.nlm.nih.gov/pubmed/17245650
http://dx.doi.org/10.1007/s11095-006-9175-2