The PDE4 inhibitor rolipram reverses object memory impairment induced by acute tryptophan depletion in the rat

RATIONALE: The selective type IV phosphodiesterase inhibitor, rolipram, has been shown to improve long-term memory and can reverse the cholinergic deficit caused by scopolamine. However, the underlying mechanisms of action of rolipram remain obscure. OBJECTIVES: The present study investigates the ef...

Descripción completa

Detalles Bibliográficos
Autores principales: Rutten, K., Lieben, C., Smits, L., Blokland, A.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2007
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1915617/
https://www.ncbi.nlm.nih.gov/pubmed/17265077
http://dx.doi.org/10.1007/s00213-006-0697-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1915617/
https://www.ncbi.nlm.nih.gov/pubmed/17265077
http://dx.doi.org/10.1007/s00213-006-0697-4

Ejemplares similares