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Simple models of genomic variation in human SNP density

BACKGROUND: Descriptive hierarchical Poisson models and population-genetic coalescent mixture models are used to describe the observed variation in single-nucleotide polymorphism (SNP) density from samples of size two across the human genome. RESULTS: Using empirical estimates of recombination rate...

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Detalles Bibliográficos
Autores principales: Sainudiin, Raazesh, Clark, Andrew G, Durrett, Richard T
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1919371/
https://www.ncbi.nlm.nih.gov/pubmed/17553150
http://dx.doi.org/10.1186/1471-2164-8-146