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Monitoring of transcriptional regulation in Pichia pastoris under protein production conditions
BACKGROUND: It has become evident that host cells react to recombinant protein production with a variety of metabolic and intrinsic stresses such as the unfolded protein response (UPR) pathway. Additionally, environmental conditions such as growth temperature may have a strong impact on cell physiol...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1919374/ https://www.ncbi.nlm.nih.gov/pubmed/17578563 http://dx.doi.org/10.1186/1471-2164-8-179 |